Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1998-01-30
2000-11-07
Chan, Christina Y.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303871, 5303881, 53038824, 4241301, 4241391, 4241411, 4241451, C07K 1622
Patent
active
06143874&
ABSTRACT:
Disclosed are nucleic acids encoding novel neurotrophic factors, designated NNT-1. Also disclosed are amino acid sequences for NNT-1 polypeptides, methods for preparing NNT-1 polypeptides, and other related aspects. Such polypeptides are active in stimulating B-cell and/or T cell production, as well as reducing inflammatory responses.
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Benigni, et al., Blood 87:5, pp. 1851-1854 (1996).
Humpel, et al.,Science, 269:552-554 [1995].
Isackson,Current Opinions in Neurobiology 5:50-357 [1995].
MacDonald and Hendrikson,Cell, 73:421-424 [1993].
Nedivi et al (Nature, 363:718-722 [1993].
Nedivi et al.,Proc. Natl. Acad. Sci USA, 93:2048-2053 [1996].
Amgen Inc
Chan Christina Y.
Cook Robert R.
Hayes Robert C.
Levy Ron K.
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