Cephalosporins having a 3-.alpha. substituted alkyl grouping

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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544 16, 544 21, 544 26, 544 28, 544 24, 544 25, 544 29, 544 30, 544 54, 542408, 542420, 26002R, 260302E, 424246, C07D50116, A61K 31545

Patent

active

040606872

ABSTRACT:
Novel cephalosporin compounds having a 3'-.alpha.-methyl, a 3-aryl or 3-heterocycle substituent are prepared by total synthesis. The novel cephalosporin compounds are active against gram-negative and gram-positive microorganisms.

REFERENCES:
patent: 3231571 (1966-01-01), Eardley et al.
patent: 3516997 (1970-06-01), Takano et al.
patent: 3819623 (1974-06-01), Takano et al.

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