Preparation of 3-benzothienylglycines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549 54, 549 55, 549 57, 549 58, C07D33360, C07D33364

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044580851

ABSTRACT:
3-Benzothienylglycines are prepared by reaction of a benzothiophene with an .alpha.-hydroxyglycine derivative in the presence of trifluoroacetic acid.

REFERENCES:
patent: 2517826 (1950-08-01), Avakian et al.
Ben-Ishai et al., Chem. Comm., J.C.S. 1975 (pp. 349-350).
Ben-Ishai et al., Tetrahedron, 32, 1976 (1571-1573).
Ben-Ishai et al., Tetrahedron, 32, 1977 (2715-2717).
Ben-Ishai et al., Tetrahedron, 34, 1978 (467-473).
Sadeh et al., J. Heterocyclic Chem., 18, 1605 (1981).

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