Processes for tigogenin beta-cellobioside

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 41, 536 5, 536 6, 536 185, 514824, C07J 5300, C07H 1524, C07H 100

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active

050101854

ABSTRACT:
Improved processes for the synthesis of tigogenin beta-cellobioside, a known hypocholesterolemic agent, using cellobiose heptaacetate and tigogenin as starting materials.

REFERENCES:
patent: 4602003 (1986-07-01), Malinow
patent: 4602005 (1986-07-01), Malinow
Liotta et al., J. Am. Chem. Soc., vol. 111, pp. 783-785 (1989).
Malinow et al., Steroids 48, 197-211 (1986).
Schmidt, Agnew. Chemie. Int. Ed. Eng. 25, 212-235 (1986).
Schmidt et al., ibid., 19, 731-732 (1980).
Schmidt et al., ibid., 21, 72-73 (1982).

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