Thiazolidinedione derivatives, method for preparing the derivati

Details Thiazolidinedione derivatives, method for preparing the derivati Thiazolidinedione derivatives, method for preparing the derivati

1996-12-18

1998-09-22

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548181, C07D41706, A61K 31425

Patent

active

058114394

ABSTRACT:
A thiazolidinedione derivative represented by the following general formula (I): ##STR1## thiazolidinedione ring residue is linked to either of 2-, 3-, 4-, 5- and 6-positions on the indole ring and R represents a group selected from the group consisting of hydrogen atom and alkyl, alkenyl, alkynyl, phenyl, aralkyl, heterocycloalkyl, arylsulfonyl and arylaminocarbonyl groups! or a pharmaceutically acceptable salt thereof exhibits excellent effects of reducing the blood sugar level and of reducing the lipid concentration in blood and is accordingly useful as a therapeutic agent for treating diabates mellitus. These derivatives and pharmaceutically acceptable salt thereof are almost free of any side effect.

REFERENCES:
patent: 5143927 (1992-09-01), Boschelli et al.
patent: 5599826 (1997-02-01), Mertens
Chemical Abstracts, vol. 73, No. 5, Aug. 3, 1970, AN-25236b.
Chemical Abstracts, vol. 75, No. 15, Oct. 11, 1971, AN-98387c.
Chemical Abstracts, vol. 113, No. 5, Jul. 30, 1990, AN-40530f.
Chemical Abstracts, vol. 116, No. 13, Mar. 30, 1992, AN-128752c.

Affiliated with

Also associated with

Rating

Thiazolidinedione derivatives, method for preparing the derivati does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thiazolidinedione derivatives, method for preparing the derivati, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thiazolidinedione derivatives, method for preparing the derivati will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1622071