Nucleic acid molecules encoding retinoblastoma protein-interacti

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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435 691, 4351723, 435410, 435243, 4353201, 435375, 435377, 536 231, 536 235, 935 22, 935 23, 935 24, 935 34, 935 66, 935 70, 935 71, C07H 2102, C12N 506, C12N 1500

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058113045

ABSTRACT:
The present invention provides a nucleic acid molecule encoding a mammalian retinoblastoma protein-interacting zinc finger (RIZ) protein, which binds retinoblastoma protein. In addition, the invention provides methods for reducing the growth of a tumor cell by introducing a nucleic acid molecule encoding a RIZ into the tumor cell.

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