Insulin derivatives, processes for their preparation and their u

Details Insulin derivatives, processes for their preparation and their u Insulin derivatives, processes for their preparation and their u

1986-06-06

1987-10-20

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 4, 530303, A61K 3726, C07K 740

Patent

active

047014407

ABSTRACT:
The invention relates to insulin derivatives of the formula I ##STR1## in which R.sup.1 denotes H or H--Phe, R.sup.30 represents the radical of a neutral L-aminoacid and R.sup.31 represents a physiologically acceptable organic group of basic character with up to 50 carbon atoms, these derivatives having an isoelectric point between 5.8 and 8.5, processes for their preparation and their use, and agents containing these derivatives for the treatment of diabetes mellitus.

REFERENCES:
Reprint from Excerpta Internation Congress Series No. 231 "Proceedings of the VII Congress of the International Diabetes Federation", Buenos Aires, Aug. 23-28, 1970.

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