Dihydrobenzofuran and related compounds useful as anti-inflammat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514345, 549345, 549462, A61K 3134, C07D30779

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active

056566611

ABSTRACT:
A compound having the structure: ##STR1## wherein (a) X is oxygen or sulfur;
(b) each Y is independently hydrogen or unsubstituted straight, branched or cyclic alkanyl having from 1 to about 3 carbon atoms,. or the two Y's are bonded to form an alkanyl ring having from 3 to about 7 carbon atoms;
(c) Z is hydrogen or unsubstituted branched or cyclic alkyl, or unsubstituted or alkanyl-substituted phenyl, having from 3 to about 10 atoms other than hydrogen;
(d) W is straight, branched or cyclic alkyl or aryl, unsubstituted or substituted, saturated or mono- or di-unsaturated with double bonds except that no terminal carbon atom of W is part of a double bond; W having from 1 to about 15 atoms other than hydrogen;
pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.

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