Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1982-07-28
1984-03-20
Siegel, Alan
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 161, 536 168, 536 179, A61K 3170, C08B 3700
Patent
active
044381077
ABSTRACT:
An aminoglycoside compound of the following formula ##STR1## wherein one of R.sub.1 and R.sub.2 represents a hydrogen atom and the other, a methyl group, R.sub.3 represents a hydrogen atom or an amino acyl group having 2 to 5 carbon atoms, R.sub.4 represents a lower alkyl group substituted by one or two substituents selected from the class consisting of hydroxy and amino groups, or a hexopyranosyl group whose hydroxy groups may be substituted by amino groups,
and a pharmaceutically acceptable acid addition salt thereof; and an antibiotic composition comprising said compound and its pharmaceutically acceptable acid addition salt.
REFERENCES:
patent: 4206206 (1980-06-01), Mori et al.
patent: 4255421 (1981-03-01), Watanabe et al.
Kamiya Kazuhiro
Mori Toshihito
Tsuchiya Tsutomu
Umezawa Hamao
Umezawa Sumio
Kowa Company Ltd.
Siegel Alan
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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