Integrin alpha subunit

Details Integrin alpha subunit Integrin alpha subunit

1996-06-14

2000-05-02

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

530327, 530328, 530329, 530330, 514 13, 514 14, 514 15, 514 16, 514 17, C07K 504, C07K 704, A61K 3804

Patent

active

060574232

ABSTRACT:
The present invention relates to a novel integrin .alpha..sup.E subunit and its functional equivalents. The method for screening a molecular library to identify lead compounds which mimick the in vivo activity of an integrin .alpha..sup.E chain is disclosed. The invention further includes pharmaceutical compositions containing the isolated peptides, oligonucleotides encoding the peptides, vectors containing the oligonucleotides, and cell lines transfected with the vectors.

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