Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-01-27
2000-05-02
Ulm, John
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 712, 43525233, 4353201, 435471, 536 235, 536 243, 935 11, 935 22, 935 70, 935 73, C12N 1512, C07K 1447, C07K 510, C07K 1563
Patent
active
060571241
ABSTRACT:
Polypeptides which bind to one or more EPH-like receptors, particularly the HEK4 receptor, are described. The polypeptides are designated HEK4 binding proteins. Nucleic acids encoding HEK4 binding proteins, and expression vectors, host cells and processes for the production of the polypeptides are also described. The polypeptides are useful for modulating the growth and/or differentiation of a variety of tissues, including those from liver, kidney, lung, skin, digestive tract and nervous system and may be used to regenerate damaged or depleted tissue and to treat cancer or nervous system disorders.
REFERENCES:
Kozlosky et al. Oncogene (Jan. 19, 1995) vol. 10. No. 2 pp. 299-306.
Fletcher et al. Oncogene (Nov. 1994) vol. 9. No. 11 pp. 3241-3247.
Bartley Timothy D.
Fox Gary M.
Amgen Inc.
Levy Ron K.
Mertz Prema
Odre Steve M.
Ulm John
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