Preparation of 1-hydropentadecafluoroadamantane and perfluoroada

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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568818, 570126, A61K 31025

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active

044029845

ABSTRACT:
Perfluoroadamantane and 1-hydropentadecafluoroadamantane are prepared by perfluorinating adamantane and/or bromoadamantane by contacting CoF.sub.3 at an elevated temperature. The fluoroadamantanes have utility as synthetic blood substitutes or perfusion media.

REFERENCES:
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patent: 4110474 (1978-08-01), Lagow et al.
patent: 4113435 (1978-09-01), Lagow et al.
patent: 4187252 (1980-02-01), Lagow et al.
patent: 4289499 (1981-09-01), Clark et al.
Maraschin et al., "J. Amer. Chem. Soc.", vol. 97#3, pp. 513-517, (1975).
Robertson et al., "J. Organic Chemistry", vol. 43, #26, pp. 4981-4983, (1978).

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