Process for statine and statine analogs

Details Process for statine and statine analogs Process for statine and statine analogs

1988-06-15

1989-10-24

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

546336, 546337, 548531, 560 39, 560 70, 560125, 562444, 562567, 564191, 564197, 564165, C07B 4304

Patent

active

048763438

ABSTRACT:
An improved process for the preparation of statine, the phenyl analog of statine, the cyclohexyl analog of statine and derivatives thereof is described, as well as other valuable intermediates used in the process.

REFERENCES:
Journal of the Chemical Society Perkin I, pp. 1177-1182.
Andrew, R. G., et al., Tetrahedron Letters, vol. 28, pp. 6535-6538 (1987).

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