CL-1957D antibiotic compound and its production

Details CL-1957D antibiotic compound and its production CL-1957D antibiotic compound and its production

1986-11-07

1987-09-29

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

435169, A61K 3574, C12D 106

Patent

active

046967940

ABSTRACT:
A purified isolate of an actinomycete identified as ATCC 39366 is capable of producing the antimicrobial compound CL-1957D.
The antimicrobial compound CL-1957D is produced by cultivating isolate ATCC 39366 under aerobic conditions in a culture medium containing assimilable sources of carbon and nitrogen until a substantial quantity of the CL-1957D compound is produced, and subsequently isolating the CL-1957D compound.
The antibiotic compound CL-1957D and pharmaceutical compositions comprising this substance together with a pharmaceutically acceptable carrier is also disclosed, as are methods of treating microbial infections in mammals, employing these pharmaceutical compositions.

REFERENCES:
patent: 4499075 (1985-02-01), Lee et al.

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