Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxyg

Details Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxyg Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxyg

1987-12-04

1989-12-26

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546269, C07D31130

Patent

active

048899410

ABSTRACT:
7-[3-[(3,4-dihydroxyphenethyl)amino]-2-hydroxypropoxy]-flavone hydrobromide, and related flavonoids are disclosed to inhibit leukotrienes and 5-lipoxygenase; preferred compounds also inhibit rat anaphylaxis.

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patent: 4668805 (1987-05-01), Wu
P. Da Re et al., J. Med. Chem., vol. 15, No. 8, pp. 868-869 (1972).
Wang Ding et al., Acta Pharm. Sinica, 15, 253 (1980).

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