Amides of retinoic acids with 5-amino tetrazole

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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424269, C07D25706, A61K 3141

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active

044594046

ABSTRACT:
5-Amino-tetrazole derivatives of retinoic acids and their physiologically tolerated salts, processes for their preparation and pharmaceutical formulations which contain these derivatives and salts and which may, in particular, be used in the treatment of dermatoses.

REFERENCES:
patent: 3256248 (1966-06-01), Lee
patent: 3950418 (1976-04-01), Bollag et al.
Staab et al., Liebigs Ann., 654 (1962), pp. 129 et seq.
Monographic: G. Plewig and A. M. Klingman, Acne-Morphogenesis and Treatment, Springer-Verlag, Heidelberg 1975.
M. B. Sporn "Chemoprevention of Cancer with Retinoids" Federation Proceedings 38 (1979), pp. 2528-2534.
S. D. Harrison, Nature 269 (1977), pp. 511-512.

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