Substituted quinoxaline-2-carboxamide 1,4-dioxides

Details Substituted quinoxaline-2-carboxamide 1,4-dioxides Substituted quinoxaline-2-carboxamide 1,4-dioxides

1974-11-19

1976-04-06

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260243B, 2602475DP, 260268C, 260307G, 260349, 424250, 424248, 424246, C07D24144

Patent

active

039489116

ABSTRACT:
Compounds of the formula ##SPC1##
Wherein X is a 6- or 7-position substituent selected from the group consisting of formyl, acetyl, hydroxymethyl, 1-hydroxyethyl and ##EQU1## wherein Y is selected from the group consisting of hydrogen and methyl; R.sub.1 is hydrogen or methyl; R.sub.2, when taken separately, is hydrogen or alkyl having 1 to 4 carbon atoms; R.sub.3, when taken separately, is hydrogen, alkyl having 1 to 4 carbon atoms, --(CH.sub.2).sub.n OH, --(CH.sub.2).sub.n OCH.sub.3, --(CH.sub.2).sub.n NH.sub.2, ##EQU2## or ##EQU3## wherein n is 2 or 3 and R.sub.2 and R.sub.3, when taken together with the nitrogen atom to which they are attached, form a member selected from the group consisting of pyrrolo, pyrrolidino, piperidino, morpholino, thiomorpholino, piperazino, N-(lower alkyl)piperazino, N-hydroxy(lower alkyl)piperazino, N-(lower alkanoyl)piperazino and N-carbo(lower alkoxy)piperazino and the pharmaceutically acceptable acid addition salts of those compounds wherein R.sub.2 has an .omega.-aminoalkyl moiety; methods for their preparation; and their use as antibacterial agents and as agents for promoting growth and improving feed efficiency of animals.

REFERENCES:
patent: 3660391 (1972-05-01), Ley
patent: 3663697 (1972-05-01), Conover
patent: 3682906 (1972-08-01), Seng
patent: 3801711 (1974-04-01), Seng
patent: 3803145 (1974-04-01), Abushanab

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