Preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as

Details Preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as Preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as

1974-08-16

1976-04-06

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D29504

Patent

active

039489000

ABSTRACT:
A process for the preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as co-products is disclosed which provides a crude reaction product free of piperazine impurity. The process of the invention comprises mixing and reacting formaldehyde and piperazine at a molar ratio of more than 1.3 to less than about 2.0 and then hydrogenating the resulting reaction product carried in methanol as a major solvent in liquid phase at a temperature of about 60.degree.-130.degree.C. in the presence of a nickel or cobalt hydrogenation catalyst. The crude hydrogenated reaction product is free from piperazine impurity from which 1-methylpiperazine and 1,4-dimethylpiperazine can be readily separated in substantially pure form such as by simple fractional distillation.

REFERENCES:
patent: 3249613 (1966-03-01), Burns et al.

Affiliated with

Also associated with

Rating

Preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of 1-methylpiperazine and 1,4-dimethylpiperazine as will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1576039