Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

1984-09-18

1986-05-06

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

424 10, 424147, 514348, 546296, 546 2, 546 6, C07D21369, A61K 31555

Patent

active

045872406

ABSTRACT:
Compounds which are a 1-hydroxypyrid-2-one in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by a substituent selected from aliphatic acyl, aliphatic amide, aliphatic amine, carboxy, cyano, aliphatic ester, halogen, hydroxy and sulpho groups, alkoxy groups and alkoxy groups substituted by an alkoxy, aliphatic amide, aliphatic amine, aliphatic ester, halogen or hydroxy group, aliphatic hydrocarbon groups and aliphatic hydrocarbon groups substituted by an alkoxy, aliphatic ester, halogen or hydroxy group, but excluding compounds in which said replacement of hydrogen atoms in the compound is effected only by substituents selected from aliphatic hydrocarbon groups, halogen groups and aliphatic hydrocarbon groups substituted by a halogen group, or a salt thereof containing a physiolgically acceptable ion or ions, are of value in the treatment of patients having a toxic concentration of a metal, particularly iron, in the body whilst the iron complexes of such compounds are of value in the treatment of iron deficiency anaemia.

REFERENCES:
patent: 2748142 (1956-05-01), Clauson-Kaas et al.
patent: 3269904 (1966-08-01), Bernstein et al.
patent: 3705943 (1972-12-01), Kaufman
patent: 3968118 (1976-07-01), Lohaus et al.
Chemical Abstracts, 1968, vol. 69, No. 35956t (Japan 67-23351), Aug. 26, 1968.
Chemical Abstracts, 1968, vol. 69, No. 35967x (Japan 67-23194), Aug. 26, 1968.
Chemical Abstracts, 1968, vol. 69, No. 35968y (Japan 67-23196), Aug. 26, 1968.
Chemical Abstracts, 1970, vol. 72, No. 12596y (Japan 69-25582), Jan. 19, 1970.
Chemical Abstracts, 1970, vol. 72, No. 132534y (Japan 70-06268), Jan. 26, 1970.
Chemical Abstracts, 1970, vol. 72, No. 132537b (Japan 70-06267), Jan. 26, 1970.
Mizukami et al and Nishimura et al, Annual Reports of the Shionogi Research Laboratories, 1966, vol. 16, pp. 29 to 36 and 37 to 40.
Shaw et al, Journal of the American Chemical Society, 1949, vol. 71, pp. 67 to 70 and 70 to 73.
Landers et al, Inorganica Chimica Acta, 1981, vol. 51, pp. 109 to 115.
Hubbard et al, Inorganic Nuclear Chemical Letters, 1979, vol. 15, pp. 255 to 258.
Pitt et al, Development of Iron Chelators for Clinical Use, Anderson and Hiller (Editors), 1975, p. 137.

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