Process for the preparation of 5,6-dihydroxyindole and intermedi

Details Process for the preparation of 5,6-dihydroxyindole and intermedi Process for the preparation of 5,6-dihydroxyindole and intermedi

1992-07-29

1995-04-25

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

558408, 558410, C07D20908, C07B 4102

Patent

active

054100674

ABSTRACT:
Process for the preparation of 5,6-dihydroxyindole, wherein the compound of formula: ##STR1## in which R' denotes a hydrogen atom or an optionally substituted benzyl radical, is subjected either to the action of hydrogen under pressure or to a hydrogen transfer operation, in a solvent medium and in the presence of a hydrogenation catalyst.

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patent: 3995041 (1976-11-01), Havera
patent: 4088763 (1978-05-01), Cyrus
patent: 4618627 (1986-10-01), Murase
Green et al., "Protecting Groups in Organic Chemistry "(1981) p. 90-91.
McOmie "Protective Groups in Organic Chemistry" (1973) pp. 168-169.
Walker, J.A.C.S. 77, 3844 (1955).
Reitz J. Med. Chem. 28, 642-647 (1985).
Muralidar, Ind. J. Chem. vol. 16B, 1004 (1978).
Translation of Japan 80/76859 (Fujimoto) (1980).
Translation of Japan 80/62061 (Ihara) (1980).

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