Method for detecting cataractogenesis using quasi-elastic light

Details Method for detecting cataractogenesis using quasi-elastic light Method for detecting cataractogenesis using quasi-elastic light

1990-01-08

1990-09-18

Cohen, Lee S.

Surgery

Truss

Pad

128745, A61B 310

Patent

active

049571133

ABSTRACT:
A method is disclosed for using quasielastic light scattering to determine the degree of cataractogenesis of a lens in vivo. By collecting and analyzing light scattered from the lens, it is possible, using the autocorrelation function or the power spectrum, to separate the fluctuations into two components: one caused by fast diffusing proteins and one caused by slow diffusing protein aggregates. This data may be applied to an experimentally determined and theoretically deduced universal curve in order to determine quantitatively the degree of cataractogenesis at that particular location in the lens.

REFERENCES:
patent: 4080264 (1978-03-01), Cohen et al.
patent: 4327973 (1982-05-01), Raif
patent: 4350163 (1982-09-01), Ford, Jr. et al.
patent: 4702576 (1987-10-01), Magnante
patent: 4711542 (1987-12-01), Ichihashi et al.
patent: 4719912 (1988-01-01), Weinberg
T. Tanaka and G. Benedek, Invest. Ophthal., 14:449-456 (1975).
T. Tanaka and C. Ishimoto, Invest. Ophthal, Visual Sci., 16:135-140 (1977).
Nishio et al., Exp. Eye Res., 39:61-68 (1984).
T. Libondi et al., Curr. Eye Res. vol. 5, 6:411-419 (1986).
M. Delaye et al., Biophys. J., 37:647-656 (1982).
Benedek, G. B., "Optical Mixing Spectroscopy with Applications in Physcis, Chemistry, Biology, and Engineering", in Polarization Matter and Radiation, Paris, 1969, Presses Universitaires, pp. 49-84.
Zeimer, R. C. and J. M. Noth, Ophthalmic Res., 16:246-225 (1984).
Weale, R. A., Exp. Eye Res., 41:457-473 (1985).
N. Clark et al., Amer. J. Physics, 38:575-585 (1970).
S. Dubin et al., Proceedings of the National Academy of Sciences, 57:1164-1171 (1967).
J. A. Jedziniak et al., Invest. Ophthal. Visual Sci., 17:51-57 (1978).
J. A. Jedziniak et al., Exp. Eye Res., 20:367-369 (1975).
J. L. Clark and G. B. Benedek, Biochem. Biophys. Res. Comm., 95:482-489 (1980).

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