Diagnosis using DCC gene

Details Diagnosis using DCC gene Diagnosis using DCC gene

1995-05-17

1997-07-22

Myers, Carla J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 4, 435 912, 435 915, 435 71, 436 86, 436 94, 436 63, 436 64, 436813, 935 77, 935 78, C12Q 168, C12P 1934, G01N 3350, G01N 33574

Patent

active

056502818

ABSTRACT:
A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.

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