Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1995-06-07
1997-10-14
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
A61K 3113, A61K 31135
Patent
active
056773501
ABSTRACT:
The present invention relates to the inhibition of cancer cell growth, proliferation, and metastasis by contacting cells with an N,N'-dibenzyl .alpha.,.omega.-diaminoalkane, a derivative of naturally-occurring putrescine. More specifically, the present invention relates to the treatment of cancer in humans by administration of a cancer cell growth-inhibiting amount of an N,N'-dibenzyl .alpha.,.omega.-diaminoalkane to a human cancer patient.
REFERENCES:
patent: 4330559 (1982-05-01), Bey et al.
patent: 4413141 (1983-11-01), Bey et al.
patent: 4499072 (1985-02-01), Sunkara et al.
patent: 4902719 (1990-02-01), Gerhart et al.
patent: 4914240 (1990-04-01), Gerhart et al.
patent: 4925835 (1990-05-01), Heston
patent: 4935449 (1990-06-01), Bey et al.
patent: 5002870 (1991-03-01), Bowlin et al.
patent: 5344846 (1994-09-01), Jakus et al.
Bolkenius, Frank N., and Seiler, Nikolaus, New Substrates of Polyamine Oxidase, Dealkylation of N-Alkyl-.alpha.-.omega.-Diamines, Biol. Chem. Hoppe-Seyler (1989), 370:525-531.
Jakus, Judit; Wolff, Edith C.; Park, Myung Hee; and Folk, J.E., Features of the Spermidine-binding Site of Deoxyhypusine Synthase as Derived from Inhibition Studies, The Journal of Biological Chemistry (1993), vol. 268, No. 18, pp. 13151-13159.
Goldberg Jerome D.
Wisconsin Alumni Research Foundation
LandOfFree
Inhibition of cancer cell growth, proliferation, and metastasis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibition of cancer cell growth, proliferation, and metastasis , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibition of cancer cell growth, proliferation, and metastasis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1555885