Styryl-substituted monocyclic and bicyclic heteroaryl compounds

Details Styryl-substituted monocyclic and bicyclic heteroaryl compounds Styryl-substituted monocyclic and bicyclic heteroaryl compounds

1995-05-19

1997-10-14

Davis, Zinna Northington

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514419, 548494, 548505, 548511, C07D20904, A61K 3140

Patent

active

056773293

ABSTRACT:
Methods of inhibiting cell proliferation in a patient suffering from such disorder comprising the use of a styryl-substituted heteroaryl compound wherein the heteroaryl group is a monocyclic ring with 1 or 2 heteroatoms, or a bicyclic ring with 1 to about 4 heteroatoms, said compound optionally substituted or polysubstituted, with the proviso that when said ring is polysubstituted, the substituents do not have a common point of attachment to said ring, and those compounds wherein no substituent on the heteroaryl group is a carboxy group or an ester group, and pharmaceutical compositions comprising such compounds.

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