Synthesis of reactive amorphous calcium phosphates

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Phosphorus or phosphorus compound

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423308, 423311, 514 2, A61K 3342, C01B 2532

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active

056769768

ABSTRACT:
The present invention provides a novel process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provides both bioactivity and structural integrity. This novel amorphous material can be reacted with other calcium phosphates at or below 37.degree. C. to form a bone-like material consisting of poorly crystalline hydroxyapatite.

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