Stable antiplaque dentifrice

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 54, 252316, A61K 716, A61K 718, A61K 722

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active

046328254

ABSTRACT:
A chemically and physically stable antiplaque dentifrice comprising an antiplaque quaternary ammonium compound, a betaine surfactant, a humectant system of glycerin and/or sorbitol and a nonionic gelling agent, prepared by a process which comprises the preparation of two separate gel phases, an oil gel phase and a water gel phase, combining said gel phases into a single gel, and adding a dental abrasive thereto as the final step, or adding said abrasive to the water gel phase prior to the addition of the oil gel phase.

REFERENCES:
patent: 2984639 (1961-05-01), Stamberger et al.
patent: 3325402 (1967-06-01), Erskine
patent: 3431208 (1969-03-01), Bailey
patent: 3703583 (1972-11-01), Martin
patent: 3842168 (1974-10-01), Colodney
patent: 3843779 (1974-10-01), Norfleet
patent: 4118476 (1978-10-01), Gaffar et al.
patent: 4188372 (1980-02-01), Gaffar
patent: 4363795 (1982-12-01), Wahlstam
patent: 4490353 (1984-12-01), Crawford et al.
"Quarternary Ammonium and Related Compounds" in the Article of Antiseptics and Disinfectants in Kirk-Othmer Encyclopedia of Chemical Technology, Second Edition, (vol. 2, pp. 632-635).

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