Therapeutically active fluoro substituted benzimidazoles

Details Therapeutically active fluoro substituted benzimidazoles Therapeutically active fluoro substituted benzimidazoles

1990-12-07

1993-12-28

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544364, C07D40112

Patent

active

052740994

ABSTRACT:
The novel compounds of the formulas I and I' ##STR1## wherein F is in 5 or 6 position and ##STR2## wherein in both formulas R is the group --CH.sub.2 OCOOR.sup.1, wherein R.sup.1 is a straight or branched alkyl containing 1-6 carbon atoms or benzyl, or R.sup.1 is the group --(CH.sub.2).sub.n ##STR3## --(CH.sub.2).sub.n COOH or --(CH.sub.2).sub.n SO.sub.3 H wherein n is 1-6 and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions containing such compounds as active ingredient, and the use of the compounds in medicine.

REFERENCES:
patent: 4965269 (1990-10-01), Brandstrom et al.
patent: 5021433 (1991-06-01), Alminger et al.

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