Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-07-02
1993-12-28
Cintins, Marianne M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
552544, C07J 7500, C07J 4300
Patent
active
052740889
ABSTRACT:
This invention relates to a method for the preparation of (25R)-26-aminocholesterol, a potent inhibitor of cholesterol biosynthesis, from (25R)-16-oxo-26-phthalimidocholesterol.
REFERENCES:
patent: 3156619 (1964-11-01), Bertin et al.
patent: 3271250 (1966-09-01), Kanazawa et al.
patent: 3291690 (1966-12-01), Bertin et al.
patent: 3839565 (1974-10-01), Saltzman
patent: 4427668 (1984-01-01), Javitt
patent: 4939134 (1990-07-01), Javitt et al.
Chemical Abstracts, vol. 79, Abstract No. 144832b (1973).
Chemical Abstracts, vol. 82, Abstract No. 13692v (1975).
Chemical Abstracts, vol. 94, Abstract No. 27444a (1981).
Chemical Abstracts, vol. 96, Abstract No. 65246m (1981).
Chemical Abstracts, vol. 98, Abstract No. 103618k (1983).
Uhle et al. (1961) J. Amer. Chem. Soc., vol. 83, pp. 1460-1472.
Brown et al., "Drugs Used in the Treatment of Hyperlipoproteinemias," Chapter 34, pp. 827-843, 1986.
G. R. Lenz in "Kirk-Othmer Concise Encyclopedia of Chemical Technology," Wiley Interscience: New York, 1986, pp. 1106-1111.
Varma et al. (1969) The Journal of Biological Chemistry, vol. 244(14), pp. 3951-3957.
Varma et al. (1975) J. Org. Chem., vol. 40(25), pp. 3680-3686.
Kandutsch et al. (1978) Science, vol. 201(11), pp. 498-501.
Tschesche et al. (1979) Chem. Ber., vol. 112, pp. 2680-2691.
Cintins Marianne M.
Kestler Kimberly J.
New York University
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