Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-06-30
1991-07-30
Scalzo, Catherine S. Kilby
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546271, A61K 3144, C07D47300
Patent
active
050360833
ABSTRACT:
The invention concerns a 1,2-dihydro-3H-indazol-3-one derivative of formula I ##STR1## wherein Ra is hydrogen, halogeno, hydroxy, cyano, trifluoromethyl, 1-6C)alkyl or (1-6C)alkoxy;
REFERENCES:
patent: 4045564 (1977-08-01), Berntsson
Chemical Abstracts Service 110: 192811 (abstract of European Patent 284,174).
Kametani et al., "Studies on the Syntheses of Azole Derivatives, Part II(1), Syntheses of N-(1- or 2-Substituted)indazolones via Diazotization (2),", Journal of Heterocyclic Chemistry, vol. 7, No. 4, Aug. 1970, pp. 815-820.
Wyrick et al., "Hypolipidemic Activity of Phthalimide Derivatives, 7, Structure-Activity Studies of Indazolone Analogues", Journal of Medicinal Chemistry, vol. 27, No. 6, Jun. 1984, pp. 768-772.
Chemical Abstracts, vol. 27, No. 21, 20th Nov. 1972, p. 451, abstract No. 140065q.
Chemical Abstracts 4-Indazolinecarboxamide, N-butyl-3-oxo- (7Cl) CAOLD (prior to 1967).
Chemical Abstracts AN CA76(24);147252m.
ICI Pharma
Imperial Chemical Industries plc
Kilby Scalzo Catherine S.
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