Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

546116, A61K 31435, C07D49804

Patent

active

052739813

ABSTRACT:
Novel compounds represented by the formula: ##STR1## wherein R represents hydrogen, alkyl radicals having from 1 to about 10 carbon atoms, alkenyl radicals having from 1 to about 10 carbon atoms, aryl, alkaryl and aralkyl radicals having from about 6 to about 16 carbon atoms and acyl and acyloxy radicals having from about 1 to about 10 carbon atoms, manifest glycosidase inhibition activity.

REFERENCES:
patent: 4260622 (1981-04-01), Junge et al.
patent: 4639436 (1987-01-01), Junge et al.
patent: 5003072 (1991-03-01), Partis et al.
patent: 5025021 (1991-06-01), Getman et al.
patent: 5026713 (1991-06-01), Getman et al.
patent: 5028614 (1991-07-01), Liu et al.
patent: 5030638 (1991-07-01), Partis et al.
patent: 5034517 (1991-07-01), Umezawa et al.
patent: 5041555 (1991-08-01), Fleet et al.
Heiker et al., Carbohydrate Res., 203(2), pp. 314-318 (Aug. 15, 1990).
Wuensche et al., Org. Mass Spectrometry, 19(4), pp. 176-182 (1984).
Heiker, F. R. et al., "Synthesis of D-galacto-1-deoxynojirimycin (1,5-dideoxy-1,5-iminoD-galactitol) Starting From 1-Deoxynojirimycin", Carbohydrate Research, 203, pp. 314-318 (1990).
Schueller, A. M. et al., "Synthesis of 2-Acetamido-1,2-ideoxy-D-galactonojirimycin(1-acetamido)-1,2,5-trideoxy-1, 5-imino-D-galactitol) From 1-Deoxynojiimycin", Carbohydrate Research, 203, pp. 308-313 (1990).
Withers, S. G. et al., "2-Deoxy-2-fluoroglucosides: A Novel Class of Mechanism-Based Glucosidase Inhibitors", J. Am. Chem. Soc., 109, pp. 7530-7531 (1987).
Bernotas, R. C. et al., "Synthesis of (+)-1,5-dideoxy-1,5-imino-D-galactitol, a potent .alpha.-D-galactosidase inhibitor", Carbohydrate Research, 167, pp. 305-311 (1987).
Wunsche, C. et al., "Comparison of `Soft Ionization` Techniques with Electron Impact Mass Spectrometry for Desoxinojirimycin and Folic Acid Derivatives", Organic Mass Spectrometry, vol. 19, No. 4, pp. 178-182 (1984).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1542842

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.