Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-04-16
1993-12-28
Dentz, Bernard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546116, A61K 31435, C07D49804
Patent
active
052739813
ABSTRACT:
Novel compounds represented by the formula: ##STR1## wherein R represents hydrogen, alkyl radicals having from 1 to about 10 carbon atoms, alkenyl radicals having from 1 to about 10 carbon atoms, aryl, alkaryl and aralkyl radicals having from about 6 to about 16 carbon atoms and acyl and acyloxy radicals having from about 1 to about 10 carbon atoms, manifest glycosidase inhibition activity.
REFERENCES:
patent: 4260622 (1981-04-01), Junge et al.
patent: 4639436 (1987-01-01), Junge et al.
patent: 5003072 (1991-03-01), Partis et al.
patent: 5025021 (1991-06-01), Getman et al.
patent: 5026713 (1991-06-01), Getman et al.
patent: 5028614 (1991-07-01), Liu et al.
patent: 5030638 (1991-07-01), Partis et al.
patent: 5034517 (1991-07-01), Umezawa et al.
patent: 5041555 (1991-08-01), Fleet et al.
Heiker et al., Carbohydrate Res., 203(2), pp. 314-318 (Aug. 15, 1990).
Wuensche et al., Org. Mass Spectrometry, 19(4), pp. 176-182 (1984).
Heiker, F. R. et al., "Synthesis of D-galacto-1-deoxynojirimycin (1,5-dideoxy-1,5-iminoD-galactitol) Starting From 1-Deoxynojirimycin", Carbohydrate Research, 203, pp. 314-318 (1990).
Schueller, A. M. et al., "Synthesis of 2-Acetamido-1,2-ideoxy-D-galactonojirimycin(1-acetamido)-1,2,5-trideoxy-1, 5-imino-D-galactitol) From 1-Deoxynojiimycin", Carbohydrate Research, 203, pp. 308-313 (1990).
Withers, S. G. et al., "2-Deoxy-2-fluoroglucosides: A Novel Class of Mechanism-Based Glucosidase Inhibitors", J. Am. Chem. Soc., 109, pp. 7530-7531 (1987).
Bernotas, R. C. et al., "Synthesis of (+)-1,5-dideoxy-1,5-imino-D-galactitol, a potent .alpha.-D-galactosidase inhibitor", Carbohydrate Research, 167, pp. 305-311 (1987).
Wunsche, C. et al., "Comparison of `Soft Ionization` Techniques with Electron Impact Mass Spectrometry for Desoxinojirimycin and Folic Acid Derivatives", Organic Mass Spectrometry, vol. 19, No. 4, pp. 178-182 (1984).
DeCrescenzo Gary A.
Getman Daniel P.
Dentz Bernard
Goetz Kenneth D.
Monsanto Company
LandOfFree
Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dide will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1542842