Retrons coding for hybrid DNA/RNA molecules

Details Retrons coding for hybrid DNA/RNA molecules Retrons coding for hybrid DNA/RNA molecules

1990-05-02

1995-04-11

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4353201, 536 232, 536 252, C12N 121, C12N 1570, C12N 1552

Patent

active

054057752

ABSTRACT:
A multicopy single-stranded DNA (msDNA) synthesizing system in E. coli is disclosed. The use of the msDNA system to synthesize cDNA in vivo is disclosed. Construction of synthetic msDNA is also disclosed. Also processes for gene amplification and for producing a stable RNA are disclosed.

REFERENCES:
Masui et al., "Multipurpose Expression Cloning Vehicles in Escherichia coli", in Experimental Manipulation of Gene Expression, Academic Press, New York, 1983, Inouye, ed., pp. 15-32.
ATCC Catalog (1985), pp. 66-79.
Yee et al. Multicopy Single-Stranded DNA Isolated from a Gram-Negative Bacterium . . . etc. Cell 38, pp. 203-209 (1984).
Dhundale et al. Distribution of Multicopy Single-Stranded DNA amoung Myxobacterial and Related Species J. Bacteriol. 164, pp. 914-917 (1985).
Furuichi T. et al. Biosynthesis and Structure of Stable Branched RNA Covalently . . . etc. Cell 48, pp. 55-62 (1987).
Dhundale et al. Structure of msDNA from M. xanthus . . . etc. Cell 51, pp. 1105-1112 (1987).
Dhundale et al. Mutations that Affect Production of Branched RNA-Linked msDNA M. xanthus . . . etc. J. Bacteriol., pp. 5620-5624 (1988).
Lim and Maas, Reverse Transcriptase-Dependent Synthesis of a Covalently Linked . . . etc. Cell 56, pp. 891-904 (Mar. 1989).

Affiliated with

Also associated with

Rating

Retrons coding for hybrid DNA/RNA molecules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Retrons coding for hybrid DNA/RNA molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retrons coding for hybrid DNA/RNA molecules will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1537937