Adiabatic off-resonance spin-locking for enhanced tumor contrast

Details Adiabatic off-resonance spin-locking for enhanced tumor contrast Adiabatic off-resonance spin-locking for enhanced tumor contrast

1994-01-24

1995-04-11

Pfaffle, Krista M.

Surgery

Truss

Pad

324309, A61B 5055

Patent

active

054048826

ABSTRACT:
Contrast between tumor and normal fat and normal fibro-glandular breast tissues is enhanced in an NMR image by a preparatory pulse sequence executed prior to the imaging pulse sequence. An off-resonance spin-locking RF pulse is employed to enhance contrast between fibro-glandular tissue and tumors and an inversion recovery sequence is employed to enhance contrast between fat and tumors.

REFERENCES:
patent: 4799015 (1989-01-01), Sepponen
patent: 4876508 (1989-10-01), Taylor
patent: 5001427 (1991-03-01), Fujiwara
patent: 5281917 (1994-01-01), Santyr
patent: 5317264 (1994-05-01), Rommel et al.
Off Resonance Field Pulsing For Contrast Manipulation In MRI: Application To Human Breast Tissues, G. E. Santyr, et al., SMRM 1988, p. 1046.
Spin Locking For Magnetic Resonance Imaging With Application To Human Breast, G. E. Santyr et al., Magnetic Resonance In Medicine 12, 25-37 (1989).

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