Stabilized aqueous amide antimicrobial composition

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424267, 424320, 424333, 424334, A01N 920

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active

041637984

ABSTRACT:
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene glycol (e.g., polyethylene glycol 200) or an ether thereof (e.g., a mono- or di- lower alkyl and/or phenyl ether) and water are stabilized against decomposition of the halogenated amide antimicrobial by the addition of an aldehyde stabilizer, such as formaldehyde, paraformaldehyde, N-formyl piperidine, vanillin, etc. The compositions so stabilized exhibit reduced rates of decomposition of the halogenated amide antimicrobial relative to the corresponding non-stabilized aqueous compositions.

REFERENCES:
patent: 3350265 (1967-10-01), Rubinstein et al.
patent: 3689660 (1972-09-01), Burk et al.
patent: 3751444 (1973-08-01), Solem et al.
patent: 4022605 (1977-05-01), Konya et al.

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