Cell agglutination reagent comprising conjugates of antibody cov

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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264 41, 264 43, 424 11, 436512, 436519, 436520, 436548, 436829, G01N 33554, G01N 33555, G01N 33563, G01N 33577

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048064661

ABSTRACT:
A number of naturally occurring antibodies to human erythrocyte surface antigens are capable of combining with their specific antigens (for example, Rhesus factor), but are not capable of producing visible hemagglutination. Also, the sensitivity of many diagnostic methods, such as in human blood typing, depends upon cell agglutination.
The present invention provides liposome-protein conjugates, especially useful for hemagglutination assays, having an enhanced agglutination capacity with respect to antibody from which the conjugates are derived.

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