17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF.sub.1.sub..alpha

Details 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF.sub.1.sub..alpha 17-Phenyl-18,19,20-trinor-cis-4,5-didehydro-PGF.sub.1.sub..alpha

1975-05-27

1977-06-28

Killos, Paul J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260520B, C07C 6976

Patent

active

040325610

ABSTRACT:
The disclosure includes novel compounds which differ from the known prostaglandins PGF.sub.2.sub..alpha., PGF.sub.2.sup..beta., PGE.sub.2, PGA.sub.2, and PGB.sub.2 in that the carbon-carbon double bond in the carboxylterminated chain of the novel compounds is in the 4,5-position rather than in the 5,6-position, and in that there is a phenyl or substituted phenyl group in the other chain of the novel compounds. These novel compounds are useful for a variety of pharmacological purposes, including abortion, labor induction, and reduction of gastric secretion.

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