Methods and compositions for the treatment of pain utilizing rop

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31445

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active

058344896

ABSTRACT:
Use of a pharmaceutically acceptable salt of ropivacaine for the manufacture of a pharmaceutical preparation with sensoric block and minimal motor blockade.

REFERENCES:
patent: 5670524 (1997-09-01), Eek
Brockway, M.S. et al., "Comparison of Extradural Ropivacaine and Bupivacaine," British Journal of Anaesthesia 66:31-37 (1991).
Concepcion, M. et al., "A New Local Anesthetic, Ropivacaine, Its Epidural Effects in Humans," Anesth. Analweg. 70:80-85 (1990).
Zaric, D. et al., "Blockade of the abdominal muscles measured by EMG during lumbar epidural analgesia with ropivacaine--a double-blind study," Acta Anaesthesiol 37:274-280 (1993).
Ropivacaine Hydrochloride, in Drugs of the Future, vol. 14, No. 8, pp. 767-771 (1989).
Wahedi et al., Regional-Anaesthesie, 13(3):57-65 (1990).
Wahedi et al., Regional-Anaesthesie, 13(3):66-72 (1990).
Zaric et al., Anesthesia and Analgesia, 73(4):509-515 (1991).
Katz et al., Biopharmaceutics & Drug Disposition, 14(7):579-588 (1993).
Wood et al., Anesthesia and Analgesia, 76(6):1274-1278 (1993).

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