Substituted imidazoles having cytokine inhibitory activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514397, 514825, 5483351, 548342, 544300, A61K 31415, C07D23354, C07D23356, C07D40102

Patent

active

058590412

ABSTRACT:
Compounds represented by formula I: ##STR1## are disclosed. .sup.AR represents an aromatic group containing 6-10 atoms; and ##STR2## represents a 4 to 10 membered non-aromatic heterocycle containing at least one N atom, and optionally containing 1-2 additional N atoms and 0-1 O or S atom. A pharmaceutical composition is also included. Methods of treating cancer and cytokine mediated diseases are also included.

REFERENCES:
patent: 3707475 (1972-12-01), Lombardino et al.
patent: 3772441 (1973-11-01), Lombardino et al.
patent: 3929807 (1975-12-01), Fitzi
patent: 3940486 (1976-02-01), Fitzi
J. L. Adams, Chem. Abs. 126 (12, Abs No. 126:144274K, 1997).

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