Polynucleotides encoding a cofactor A-like protein

Details Polynucleotides encoding a cofactor A-like protein Polynucleotides encoding a cofactor A-like protein

1997-04-08

1998-11-10

Kemmerer, Elizabeth C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 4353201, 435325, 435 6, 536 235, C12N 1512, C12N 510, C12Q 168, C07H 2104

Patent

active

058342397

ABSTRACT:
The present invention provides a human cofactor A-like protein (COAPR) and polynucleotides which identify and encode COAPR. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of COAPR.

REFERENCES:
Wynn, R.M. et al., "Molecular chaparones: Heat-shock proteins, foldases, and matchmakers", J. Lab. Clin. Bed., (1994) 124: 31-36.
Govezensky, D. et al., "Chaperonins as potential gene regulatory factors", J. Biol. Chem., (1994) 269: 14003-14006.
Gething, M.A. et al., "Protein folding in the cell", Nature, (1992) 355:33-45.
Gao, Y. et al., "Two cofactors and cytoplasmic chaperonin are required for the folding of .alpha.-and .beta.-Tubulin", Mol. Cell Biol., (1993) 13: 2478-2480.
Melki, R. et al., "Cofactor A is a molecular chaperone required for .beta.-Tubulin folding: Functional and structual characterization", Biochem., (1996) 35: 10422-10435.
Gao, Y. et al., "A novel cochaperonin that modulates the ATPase activity of cytoplasmic chaperonin", J. Cell Biol., (1994) 125: 989-996.
Gao, Y. et al., "A cytoplasmic chaperonin that catalyzes .beta.-Actin folding", Cell, (1992) 69: 1043-1050.

Affiliated with

Also associated with

Rating

Polynucleotides encoding a cofactor A-like protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polynucleotides encoding a cofactor A-like protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polynucleotides encoding a cofactor A-like protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1515478