Formation of triple helix complexes of single stranded nucleic a

Details Formation of triple helix complexes of single stranded nucleic a Formation of triple helix complexes of single stranded nucleic a

1994-11-21

1998-11-10

Marschel, Ardin H.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

436501, 514 44, 536 253, 935 77, 935 78, C12Q 168

Patent

active

058341854

ABSTRACT:
Methods of detecting, recognizing or inhibiting or altering expression of a target sequence of a single stranded nucleic acid having any combination of purine and pyrimidine nucleosides by formation of triple helix complexes in conjunction with Second and Third Strands which comprise optionally covalently linked Oligomers are provided.

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patent: 5422251 (1995-06-01), Fresco
Stein et al. (1993) Science, vol. 261, pp. 1004-1012.
Le Doan et al. (1987) Nuc. Acids Res., vol. 15, No. 19, pp. 7749-7760.
Howard et al. (1976) Biochemistry, vol. 15, No. 17, pp. 3783-3795.
New England Biolabs Catalog (New England Biolabs, Beverly, MA, USA, 1986/1987) pp. 60-62.
Kan et al. (1992) FASEB J., vol. 6, No. 1, p. A424.
Ono et al. (1991) J. Am. Chem. Soc., vol. 113, pp. 4032-4033.
New England Biolabs Catalog (1986/1987) (New England Biolabs, Mass., USA) pp. 60-61.

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