Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1997-07-08
1999-01-12
Duffy, Patricia
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 435325, 435243, 4352534, 536 231, 536 237, C12P 2106, C12N 1500, C12N 100, C07H 2104
Patent
active
058587187
ABSTRACT:
The invention provides pcrA polypeptides and DNA (RNA) encoding pcrA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pcrA polypeptides to screen for antibacterial compounds.
REFERENCES:
Iordanescu, S., "Characterization of the Staphylococcus aureus chromosomal gene per A, identified by mutations affecting plasmid pT181 replication" Mol Gen Genet (1993) 241: 185-192.
Iordanescu, S. and Bargonetti, J., "Staphylococcus aureus Chromosomal Mutations That Decrease Efficiency of Rep Utilization in Replication of pT181 and Related Plasmids" Journal of Bacteriology, Aug. 1989 , p. 4501-4503.
Iordanescu, S. and Bargonetti, J., Genbank Submission, Accession No. M63176, Jan. 24, 1994.
Black Michael Terence
Hodgson John Edward
Holmes David J.
Knowles David Justin Charles
Lonetto Michael Arthur
Duffy Patricia
Gimmi Edward R.
Jackson Arthur E.
King William T.
SmithKline Beecham Corporation
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