HIV protease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514300, 514301, 514302, 514303, 546114, 546115, 546146, A61K 3147, C07D21706, C07D21712, C07D47102

Patent

active

059523433

ABSTRACT:
HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

REFERENCES:
patent: 5063208 (1991-11-01), Rosenberg et al.
patent: 5142056 (1992-08-01), Kempe et al.
patent: 5157041 (1992-10-01), Handa et al.
patent: 5196438 (1993-03-01), Martin et al.
patent: 5204471 (1993-04-01), Negele et al.
patent: 5235039 (1993-08-01), Heath, Jr. et al.
Tam et al., J. Med. Chem., 35(7):1318-1320 (1992).
Huff, J. Med. Chem., 34(8):2305-2314 (1991).
Ghosh et al., J. Med. Chem., 36(2):292-294 (1993).
Ghosh et al., J. Med. Chem., 36(16):2300-2310 (1993).
Thompson et al., J. Am. Chem. Soc., 115(2):801-802 (1993).
Rich et al., J. Med. Chem., 34(3):1222-1225 (1991).
Thaisvivongs et al., J. Med. Chem., 34:2344-2356 (1991).
Ghosh et al., J. Med. Chem., 36:924-927 (1993).
Chong et al., J. Med. Chem., 36:2575-2577 (1993).
Vava Pradad et al., Peptides, Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium, Jun. 16-21, pp. 721-722 (1991).
Rich, et al., Chem. Abstracts, 114(15) Abstract No. 143998q (1991).
Houpis et al., Tetrahedron Letters, 34(16):2593-2596 (1993).
Roberts, N.A. et al., Science, 248:358-361 (1990).
Gilbert et al., J. Chem. Soc. Perkin Trans., 2:475-479 (1993).
Young et al., J. Med. Chem., 35:1702-1709 (1992).
Lyle et al., J. Med. Chem., 34:1228-1230 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

HIV protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with HIV protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and HIV protease inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1510021

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.