Flea nucleic acid sequences and uses thereof

Details Flea nucleic acid sequences and uses thereof Flea nucleic acid sequences and uses thereof

1996-08-01

1999-09-14

Allen, Marianne P.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 536 235, 536 2432, C12N 1512

Patent

active

059521945

ABSTRACT:
The present invention relates to ectoparasite histamine releasing factor (HRF) proteins; to ectoparasite HRF nucleic acid molecules, including those that encode such HRF proteins; to antibodies raised against such HRF proteins; and to compounds that inhibit ectoparasite HRF activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to reduce ectoparasite burden of animals.

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Toki, et al., Biomed. Res., 9(1):75-79, 1988.
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Wanstall, et al., Toxicon, 12:649-655, 1974.
Gross, B. et al., NAR, 17(20):8367, 1989.

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