Adjuvant formulation with enhanced immunogenic activity, and rel

Details Adjuvant formulation with enhanced immunogenic activity, and rel Adjuvant formulation with enhanced immunogenic activity, and rel

1995-06-05

1999-09-14

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

4241841, 4242041, 4242341, 4242831, 514642, A61K 3900, A61K 4500

Patent

active

059519886

ABSTRACT:
Adjuvant formulations are provided containing quaternary ammonium salts in conjunction with an oil component which may be a mineral oil, an animal oil, a vegetable oil, a mixture thereof, or an oil-in-water emulsion of one or more of such oils. These formulations are useful in conjunction with known immunological substances, e.g., viral or bacterial antigens in a vaccine composition, in order to enhance the immunogenic response. The compositions are also useful without an incorporated antigen as nonspecific immunostimulatory formulations.

REFERENCES:
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patent: 4395394 (1983-07-01), Wolff, III et al.
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