Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1992-01-16
1996-07-02
Schwartz, Richard A.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
5303879, G01N 33538, C07K 1618
Patent
active
055321690
ABSTRACT:
A method of determining collagen degradation in vivo, comprising quantitating the concentration of a peptide in a body fluid, the peptide being a C-terminal type II collagen telopeptide containing a hydroxylysyl pyridinoline cross-link or a type III collagen telopeptide containing a hydroxylysyl pyridinoline cross-link. The method includes immunometric assays, fluorometric assays, and electrochemical titrations for quantitation. The structures of specific peptides having cross-links and kits for quantitating these peptides in a body fluid are described.
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Ketter James
Schwartz Richard A.
Washington Research Foundation
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