Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-08-25
1996-01-23
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 721, 435 723, 435 732, 4352871, 436526, 436806, 436808, 324200, 324228, 324244, G01N 3353
Patent
active
054864577
ABSTRACT:
Mechanical stresses and deformations are applied directly to cell surface receptors or molecules and measured using a system including a magnetic twisting device in combination with ferromagnetic microbeads coated with ligands for integrins or any other surface receptors. The system can be used diagnostically to characterize cells and molecules and to determine the effect of transformation and compounds, including drugs, on the cells and molecules. The system can also be used to induce cells to grow or alter production of molecules by the cells.
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Butler James P.
Fredberg Jeffrey J.
Ingber Donald E.
Wang Ning
Children's Medical Center Corporation
President and Fellows of Harvard College
Scheiner Toni R.
Wolski Susan C.
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