Method for treating insulin resistance

Details Method for treating insulin resistance Method for treating insulin resistance

1994-12-01

1996-10-01

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514866, A61K 3113

Patent

active

055611656

ABSTRACT:
A method is provided for increasing insulin responsiveness and improving glucose tolerance in a mammal comprising administration of an effective amount of a cholinergic agonist; pharmaceutical compositions are also provided.

REFERENCES:
patent: 5035887 (1991-07-01), Ayer et al..
The Merck Index, 9th Ed, 1976, Nos. 12, 15, 78, 79 & 5793-5795.
Blei et al., (1982), "Insulin Resistance and Insulin Receptors in Hepatic Cirrhosis." Gastroenterology, 83, 1191-9.
Lautt, W. W., (1980), "Hepatic Parasympathetic Neuropathy As Cause Of Maturity-Onset Diabetes?." Gen. Pharmac., 11, 343-345.
Mondon, C., Burton, S., (1971), "Factors Modifying Carbohydrate Metabolism And Effect Of Insulin In Perfused Rat Liver." Amer. J. Physiol., 220(3), 724-733.
Schafer et al., (1993), "Hepatic Blood Volume Responses and Compliance in Cats with Long-term Bile Duct Ligation." Hepatology, 18(4), 969-977.
Xie, et al., (1992), "Insulin Resistance Of Glucose Response Produced By Hepatic Denervations." Can. J. Pharmacol., 71, 175-178.

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