Transdermal matrix system

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424448, A61F 1300

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active

047895470

ABSTRACT:
A composition for the transmembranal, including transdermal, administration of a pharmaceutical preparation comprising cross-linked carboxymethylcellulose, an alcohol soluble poly (2-hydroxyethyl) methacrylate), a permeation enhancer, such as a mixture of linoleic acid and propylene glycol, and a biologically active material, as well as a device for administering the aforementioned composition to mammals, and also a method for administering transdermally to a mammal an effective amount of the aforementioned composition.

REFERENCES:
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patent: 4056496 (1977-11-01), Mancini et al.
patent: 4226848 (1986-10-01), Yoshida
patent: 4250163 (1981-02-01), Nagai
patent: 4359483 (1982-11-01), Katesu
patent: 4423099 (1983-12-01), Mueller
patent: 4435412 (1984-03-01), Girijavallabhan
patent: 4435413 (1984-03-01), McCombie
patent: 4452892 (1984-06-01), Rosevear
patent: 4563182 (1986-01-01), Stoy
patent: 4575539 (1986-03-01), DeCosta et al.
patent: 4666703 (1987-05-01), Kopf
patent: 4668506 (1987-05-01), Bawa
U.S. patent application Ser. No. 900,865, filed Aug. 27, 1986, (PD-3371), M. Mahjour, et al.

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