Preparation of 7-(3-amino- and 3-amino-methyl-1-pyrrolidinyl)-3-

Details Preparation of 7-(3-amino- and 3-amino-methyl-1-pyrrolidinyl)-3- Preparation of 7-(3-amino- and 3-amino-methyl-1-pyrrolidinyl)-3-

1991-06-19

1997-07-15

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546123, 546146, C07D215233, C07D40104

Patent

active

056484933

ABSTRACT:
Process for the preparation of antibacterial compounds of the formula ##STR1## comprises condensing an oxo compound of the formula ##STR2## with an amino compound of the formula ##STR3## to produce a compound of the formula ##STR4## reacting the compound of the formula (III) with a compound of the formula ##STR5## to give a compound of the formula ##STR6## and then eliminating the amino-protective group ##STR7##

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patent: 4762845 (1988-08-01), Chu et al.
patent: 4780468 (1988-10-01), Bridges
patent: 4962112 (1990-10-01), Rosen et al.
H. Beyer, Textbook of Organic Chemistry (1978), p. 145.
Houben Weyl, Methods of Organic Chemistry, vol. XI/1, pp. 24-27, 1957.
Chemical Abstracts, vol. 105, No. 23, Abstract 208,850w, Dec. 8, 1986, p. 593.
Chemical Abstracts, vol. 107, No. 9, Abstract 77,777u, Aug. 31, 1987, p. 703.

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