Process for the preparation of aminotriazine derivatives

Details Process for the preparation of aminotriazine derivatives Process for the preparation of aminotriazine derivatives

1995-06-02

1997-07-15

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D25306

Patent

active

056484879

ABSTRACT:
A process for the preparation of a compound of the formula ##STR1## where Z and R are defined herein. A compound of formula II ##STR2## where R.sub.1 defined herein, is reacted with hydrazine hydrate and then subjected to hydrolysis to form the compound of formula I ##STR3## and the compound of the formula I is reacted with the aldehyde of the formula ##STR4## into the resulting compound of the formula IV.

REFERENCES:
patent: 4931419 (1990-06-01), Kristinsson
patent: 4996325 (1991-02-01), Kristinsson
patent: 5179094 (1993-01-01), Kristiansen et al.
Chem. Abst. 83:131552Z, (1975) Hetzheim et al.
Chem. Abst. 67:6449v, (1967) Hetzheim et al.
Chem. Abst. 75:129769K (1971) Hetzheim et al.
Chem. Abst. 91:211409g (1979) Takano.
Magnetic Resonance in Chemistry, ".sup.15 N and .sup.13 C NMR Study, etc", Fritz et al., vol. 28, 331-336 (1990).

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