Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-06
1997-07-15
Chan, Christina Y.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 691, 536 231, 536 236, C12P 2106, C07H 2104
Patent
active
056482426
ABSTRACT:
The invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of a P14 allergen of birch Betula verrucosa and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. A method is provided that permits purification of P14 allergens or cross reactive allergens by means of binding to poly(L-proline). In addition, methods are described for making the proteins and polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of diseases.
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Breitenbach Michael
Duchene Michael
Kraft Dietrich
Pettenburger Karin
Rumpold Helmut
Biomay Produktions - Und Handelsgesellschaft M.B.H.
Chan Christina Y.
Nolan Patrick J.
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